UTIs occur when harmful microbes make their way into the lower or upper urinary tract. Lower UTIs, which occur in the urethra and bladder, are most common. These are also called cystitis. In most cases, the bacteria that invade the lower urinary tract come from our own bodies. E. Coli, which normally lives in the intestine, is the most common and can infect the urinary tract when the urethra is exposed to bacteria from faeces.
Highly virulent bacteria that are left untreated can spread up through the ureters to one, or both kidneys, and cause an upper UTI. Symptoms of this could be back pain, nausea and fever. If it is left untreated it can potentially damage the kidneys, or even cause kidney failure. In some cases, the kidney infection can spread to the blood stream, causing urosepsis, which requires immediate intensive care. If an upper or lower UTI has been diagnosed and treatment is needed, the doctor will decide which antibiotic and dosage to prescribe.
Asymptomatic Bacteriuria, also referred to as "friendly" bacteria, in the urinary tract, is a harmless condition that should not be treated with antibiotics. These bacteria will show no symptoms except for smelly urine in some people.